MolNFT v1 · #386057 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit D (Q8U0E4)

Q8U0E4: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit D (Q8U0E4)”. 1 pocket (best druggability 0.29). MolNFT v1 #386057 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8U0E4
Type: protein
Length: 261 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x33518602616d09288Bc21CC74d137782b749EFb2
Molecule: DNA-directed RNA polymerase subunit D
UniProt: Q8U0E4
Pockets: 1 · best druggability 0.29

Structure

1 distinct chain · 28% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase subunit D	protein	261	28% helix, 38% strand	Q8U0E4

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.29	0.74	14	empty

Compared structures

8RBO · Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp… · an experimental structure of the same protein · chain A against D, TM-score 0.96
8OKI · Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5 · an experimental structure of the same protein · chain A against D, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8U0E4
Elsewhere: UniProt Q8U0E4 · AlphaFold DB Q8U0E4

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