MolNFT v1 · #386005 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit a'' (Q5JE34)
Q5JE34: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit a'' (Q5JE34)”. 3 pockets (best druggability 0.59). MolNFT v1 #386005 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5JE34
- Type
- protein
- Length
- 391 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF8cD1d8d93E9783063700De244A6e3cf6A195579
- Molecule
- DNA-directed RNA polymerase subunit a''
- UniProt
- Q5JE34
- Pockets
- 3 · best druggability 0.59
Structure
1 distinct chain · 47% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit a'' | protein | 391 | 47% helix, 14% strand | Q5JE34 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 395 | 0.59 | 0.76 | 46 | empty |
| 2 | 183 | 0.45 | 0.74 | 24 | empty |
| 3 | 103 | 0.41 | 0.77 | 16 | empty |
Compared structures
- 9BCU · Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription… · an experimental structure of the same protein · chain A against C, TM-score 0.91
- 9BCT · Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription… · an experimental structure of the same protein · chain A against C, TM-score 0.90
- 6KF3 · Cryo-EM structure of Thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against C, TM-score 0.86
- 6KF3 · Cryo-EM structure of thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against C, TM-score 0.86
- 6KF4 · Cryo-EM structure of Thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against C, TM-score 0.85
- 6KF4 · Cryo-EM structure of thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against C, TM-score 0.85
- 6KF9 · Cryo-EM structure of thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against C, TM-score 0.85
- 6KF9 · Cryo-EM structure of Thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against C, TM-score 0.85
- 4QIW · Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis · an experimental structure of the same protein · chain A against C, TM-score 0.85
- 4QIW · Crystal structure of euryarchaeal RNA polymerase from thermococcus kodakarensis · an experimental structure of the same protein · chain A against C, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5JE34
- Elsewhere: UniProt Q5JE34 · AlphaFold DB Q5JE34
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