UniProt Q5JE34
DNA-directed RNA polymerase subunit A'' (Q5JE34)
DNA-directed RNA polymerase subunit A'' (UniProt Q5JE34), EC 2.7.7.6: 10 experimental structures and 1 predicted model on GenesisL1, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5JE34
- Protein
- DNA-directed RNA polymerase subunit A''
- EC
- 2.7.7.6
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 38 · 6 records with a druggable one
Structures
11 records of Q5JE34 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4QIW | Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis | x-ray diffraction | C, M | — | — |
| 4QIW | Crystal structure of euryarchaeal RNA polymerase from thermococcus kodakarensis | x-ray diffraction | C, M | — | — |
| 6KF3 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | C | — | 7 (best 0.78) |
| 6KF3 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | C | — | — |
| 6KF4 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | C | — | 9 (best 0.80) |
| 6KF4 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | C | — | — |
| 6KF9 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | C | — | 9 (best 0.79) |
| 6KF9 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | C | — | — |
| 9BCT | Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex… | electron microscopy | C | — | 5 (best 0.80) |
| 9BCU | Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex… | electron microscopy | C | — | 5 (best 0.80) |
| Q5JE34 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit a'' (Q5JE34) | predicted | A | — | 3 (best 0.59) |
Experiment against prediction
- 9BCU chain C against the predicted model Q5JE34: TM-score 0.94, RMSD 1.96 Å
- 9BCT chain C against the predicted model Q5JE34: TM-score 0.93, RMSD 2.01 Å
- 4QIW chain C against the predicted model Q5JE34: TM-score 0.90, RMSD 2.56 Å
- 4QIW chain C against the predicted model Q5JE34: TM-score 0.90, RMSD 2.56 Å
- 6KF3 chain C against the predicted model Q5JE34: TM-score 0.86, RMSD 2.82 Å
- 6KF3 chain C against the predicted model Q5JE34: TM-score 0.86, RMSD 2.82 Å
- 6KF4 chain C against the predicted model Q5JE34: TM-score 0.86, RMSD 2.89 Å
- 6KF4 chain C against the predicted model Q5JE34: TM-score 0.86, RMSD 2.89 Å
- 6KF9 chain C against the predicted model Q5JE34: TM-score 0.86, RMSD 2.98 Å
- 6KF9 chain C against the predicted model Q5JE34: TM-score 0.86, RMSD 2.98 Å
Elsewhere
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