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MolNFT v1 · #385932 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit L (Q5JE88)

Q5JE88: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit L (Q5JE88)”. 1 pocket (best druggability 0.32). MolNFT v1 #385932 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q5JE88
Type
protein
Length
94 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xEa58c7534E5701aA8370E0fAEb19b7e14653e69c
Molecule
DNA-directed RNA polymerase subunit L
UniProt
Q5JE88
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 41% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerase subunit Lprotein9441% helix, 29% strandQ5JE88

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1580.320.7513empty

Compared structures

  • 9BCT · Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription… · an experimental structure of the same protein · chain A against L, TM-score 0.98
  • 9BCU · Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription… · an experimental structure of the same protein · chain A against L, TM-score 0.98
  • 4QIW · Crystal structure of euryarchaeal RNA polymerase from thermococcus kodakarensis · an experimental structure of the same protein · chain A against L, TM-score 0.95
  • 4QIW · Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis · an experimental structure of the same protein · chain A against L, TM-score 0.95
  • 6KF3 · Cryo-EM structure of Thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against L, TM-score 0.94
  • 6KF3 · Cryo-EM structure of thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against L, TM-score 0.94
  • 6KF9 · Cryo-EM structure of thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against L, TM-score 0.94
  • 6KF9 · Cryo-EM structure of Thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against L, TM-score 0.94
  • 4QJV · The X-ray crystal structure of RPO3/RPO11 heterodimer of euryarchaeal RNA polymerase from… · an experimental structure of the same protein · chain A against B, TM-score 0.94
  • 4QJV · The X-ray crystal structure of Rpo3/Rpo11 heterodimer of euryarchaeal RNA polymerase from… · an experimental structure of the same protein · chain A against B, TM-score 0.94
  • 6KF4 · Cryo-EM structure of thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against L, TM-score 0.94
  • 6KF4 · Cryo-EM structure of Thermococcus kodakarensis RNA polymerase · an experimental structure of the same protein · chain A against L, TM-score 0.94

Analyse

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