UniProt Q5JE88
DNA-directed RNA polymerase subunit L (Q5JE88)
DNA-directed RNA polymerase subunit L (UniProt Q5JE88), EC 2.7.7.6: 12 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5JE88
- Protein
- DNA-directed RNA polymerase subunit L
- EC
- 2.7.7.6
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 6 · 5 records with a druggable one
Structures
13 records of Q5JE88 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4QIW | Crystal structure of euryarchaeal RNA polymerase from Thermococcus kodakarensis | x-ray diffraction | L, U | — | — |
| 4QIW | Crystal structure of euryarchaeal RNA polymerase from thermococcus kodakarensis | x-ray diffraction | L, U | — | — |
| 4QJV | The X-ray crystal structure of Rpo3/Rpo11 heterodimer of euryarchaeal RNA polymerase from… | x-ray diffraction | B, D | — | — |
| 4QJV | The X-ray crystal structure of RPO3/RPO11 heterodimer of euryarchaeal RNA polymerase from… | x-ray diffraction | B, D | — | — |
| 6KF3 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | L | — | 1 (best 0.77) |
| 6KF3 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | L | — | — |
| 6KF4 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | L | — | 1 (best 0.76) |
| 6KF4 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | L | — | — |
| 6KF9 | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | electron microscopy | L | — | 1 (best 0.79) |
| 6KF9 | Cryo-EM structure of thermococcus kodakarensis RNA polymerase | electron microscopy | L | — | — |
| 9BCT | Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex… | electron microscopy | L | — | 1 (best 0.76) |
| 9BCU | Cryo-EM structure of Thermococcus kodakarensis FttA-dependent transcription pre-termination complex… | electron microscopy | L | — | 1 (best 0.76) |
| Q5JE88 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit L (Q5JE88) | predicted | A | — | 1 (best 0.32) |
Experiment against prediction
- 9BCT chain L against the predicted model Q5JE88: TM-score 0.98, RMSD 0.54 Å
- 9BCU chain L against the predicted model Q5JE88: TM-score 0.98, RMSD 0.57 Å
- 4QJV chain D against the predicted model Q5JE88: TM-score 0.96, RMSD 0.77 Å
- 4QJV chain D against the predicted model Q5JE88: TM-score 0.96, RMSD 0.77 Å
- 4QIW chain L against the predicted model Q5JE88: TM-score 0.95, RMSD 0.84 Å
- 4QIW chain L against the predicted model Q5JE88: TM-score 0.95, RMSD 0.84 Å
- 6KF3 chain L against the predicted model Q5JE88: TM-score 0.94, RMSD 0.92 Å
- 6KF3 chain L against the predicted model Q5JE88: TM-score 0.94, RMSD 0.92 Å
- 6KF9 chain L against the predicted model Q5JE88: TM-score 0.94, RMSD 0.97 Å
- 6KF9 chain L against the predicted model Q5JE88: TM-score 0.94, RMSD 0.97 Å
Elsewhere
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