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MolNFT v1 · #385027 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 9A (Q6NLH0)

Q6NLH0: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 9A (Q6NLH0)”. 1 pocket (best druggability 0.34). MolNFT v1 #385027 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q6NLH0
Type
protein
Length
114 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
Molecule
DNA-directed RNA polymerases II, IV and V subunit 9A
UniProt
Q6NLH0
Pockets
1 · best druggability 0.34

Structure

1 distinct chain · 5% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerases II, IV and V subunit 9Aprotein1145% helix, 30% strandQ6NLH0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1680.340.7613empty

Compared structures

  • 8XMC · Post-translocated Pol IV transcription elongation complex · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 8XMD · Pre-translocated Pol IV transcription elongation complex · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 8XME · Backtracked Pol IV transcription elongation complex · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 7EU0 · The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 7EU0 · The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 8XMB · NTP-bound Pol IV transcription elongation complex · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 7EU1 · The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 7EU1 · The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme · an experimental structure of the same protein · chain A against I, TM-score 0.46
  • 8HYJ · A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex · an experimental structure of the same protein · chain A against I, TM-score 0.39

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