UniProt Q6NLH0
DNA-directed RNA polymerases II, IV and V subunit 9A (Q6NLH0)
DNA-directed RNA polymerases II, IV and V subunit 9A (UniProt Q6NLH0): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q6NLH0
- Protein
- DNA-directed RNA polymerases II, IV and V subunit 9A
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 28 · 7 records with a druggable one
Structures
10 records of Q6NLH0 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EU0 | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | electron microscopy | I | ZN | 4 (best 0.79) |
| 7EU0 | The cryo-EM structure of a. thaliana pol IV-RDR2 backtracked complex | electron microscopy | I | ZN | — |
| 7EU1 | The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme | electron microscopy | I | ZN | 5 (best 0.79) |
| 7EU1 | The cryo-EM structure of a. thaliana pol IV-RDR2 holoenzyme | electron microscopy | I | ZN | — |
| 8HYJ | A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex | electron microscopy | I | ZN | 1 (best 0.72) |
| 8XMB | NTP-bound Pol IV transcription elongation complex | electron microscopy | I | ZN | 4 (best 0.81) |
| 8XMC | Post-translocated Pol IV transcription elongation complex | electron microscopy | I | ZN | 4 (best 0.81) |
| 8XMD | Pre-translocated Pol IV transcription elongation complex | electron microscopy | I | ZN | 5 (best 0.81) |
| 8XME | Backtracked Pol IV transcription elongation complex | electron microscopy | I | ZN | 4 (best 0.81) |
| Q6NLH0 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases II, IV and V subunit 9A (Q6NLH0) | predicted | A | — | 1 (best 0.34) |
Ligands
- ZN · Zinc ion · in 9 records
Experiment against prediction
- 8XMC chain I against the predicted model Q6NLH0: TM-score 0.47, RMSD 3.00 Å
- 8XMD chain I against the predicted model Q6NLH0: TM-score 0.47, RMSD 3.03 Å
- 8XME chain I against the predicted model Q6NLH0: TM-score 0.47, RMSD 3.05 Å
- 7EU0 chain I against the predicted model Q6NLH0: TM-score 0.46, RMSD 3.23 Å
- 7EU0 chain I against the predicted model Q6NLH0: TM-score 0.46, RMSD 3.23 Å
- 8XMB chain I against the predicted model Q6NLH0: TM-score 0.46, RMSD 3.44 Å
- 7EU1 chain I against the predicted model Q6NLH0: TM-score 0.46, RMSD 3.53 Å
- 7EU1 chain I against the predicted model Q6NLH0: TM-score 0.46, RMSD 3.53 Å
- 8HYJ chain I against the predicted model Q6NLH0: TM-score 0.45, RMSD 2.49 Å
Elsewhere
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