MolNFT v1 · #384825 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA1 (P28363)

P28363: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA1 (P28363)”. 9 pockets (best druggability 0.62). MolNFT v1 #384825 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P28363
Type: protein
Length: 638 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x8D2e4Aa2bf04A7561b24Ce08Ad813be6bD22A2B0
Molecule: DNA-directed RNA polymerase I subunit RPA1
UniProt: P28363
Pockets: 9 · best druggability 0.62

Structure

1 distinct chain · 46% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase I subunit RPA1	protein	638	46% helix, 14% strand	P28363

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	321	0.62	0.78	32	empty
2	147	0.56	0.82	30	empty
3	147	0.53	0.80	25	empty
4	215	0.48	0.75	25	empty
5	98	0.46	0.80	25	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P28363
Elsewhere: UniProt P28363 · AlphaFold DB P28363

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