GL1X · GenesisL1 explorer

MolNFT v1 · #381915 · protein

AlphaFold monomer V2.0 prediction for ribonuclease hii (O74035)

O74035: “AlphaFold monomer V2.0 prediction for ribonuclease hii (O74035)”. 1 pocket (best druggability 0.34). MolNFT v1 #381915 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O74035
Type
protein
Length
228 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xEc4C90d408De7142a2936ac29701e3ce1373d0a4
Molecule
Ribonuclease hii
UniProt
O74035
Pockets
1 · best druggability 0.34

Structure

1 distinct chain · 55% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibonuclease hiiprotein22855% helix, 16% strandO74035

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1840.340.7516empty

Compared structures

  • 2DFH · Crystal structure of Tk-RNase HII(1-212)-C · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 2DFH · Crystal structure of tk-RNase HII(1-212)-C · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 1IO2 · Crystal structure of type 2 ribonuclease H from hyperthermophilic archaeon, thermococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 1IO2 · Crystal structure of type 2 ribonuclease h from hyperthermophilic archaeon, thermococcus… · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 2DFF · Crystal structure of tk-RNase HII(1-204)-C · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 2DFF · Crystal structure of Tk-RNase HII(1-204)-C · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 2DFE · Crystal structure of Tk-RNase HII(1-200)-C · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 2DFE · Crystal structure of tk-RNase HII(1-200)-C · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 1X1P · Crystal structure of Tk-RNase HII(1-197)-A(28-42) · an experimental structure of the same protein · chain A against A, TM-score 0.84
  • 1X1P · Crystal structure of tk-RNase HII(1-197)-A(28-42) · an experimental structure of the same protein · chain A against A, TM-score 0.84

Analyse

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