MolNFT v1 · #381249 · protein
AlphaFold monomer V2.0 prediction for ribonuclease H1 (O60930)
O60930: “AlphaFold monomer V2.0 prediction for ribonuclease H1 (O60930)”. 3 pockets (best druggability 0.70). MolNFT v1 #381249 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60930
- Type
- protein
- Length
- 286 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4141a28d01903C0B64b4D81154B91A04f2dcBe49
- Molecule
- Ribonuclease H1
- UniProt
- O60930
- Pockets
- 3 · best druggability 0.70
Structure
1 distinct chain · 27% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonuclease H1 | protein | 286 | 27% helix, 17% strand | O60930 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 209 | 0.70 | 0.87 | 26 | empty |
| 2 | 78 | 0.33 | 0.75 | 16 | empty |
| 3 | 57 | 0.30 | 0.74 | 11 | empty |
Compared structures
- 2QK9 · Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2QK9 · Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2QKB · Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2QKB · Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 2QKK · Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 2QKK · Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 8SWC · RNase H complex with ASO (OOO) and RNA · an experimental structure of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60930
- Elsewhere: UniProt O60930 · AlphaFold DB O60930
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