MolNFT v1 · #378245 · protein
AlphaFold monomer V2.0 prediction for dual-specificity RNA methyltransferase rlmn (A7ZPW0)
A7ZPW0: “AlphaFold monomer V2.0 prediction for dual-specificity RNA methyltransferase rlmn (A7ZPW0)”. 4 pockets (best druggability 0.83). MolNFT v1 #378245 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A7ZPW0
- Type
- protein
- Length
- 384 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xFE04EC045E1BA245Bec1eE3dfF31a8B2Daf70d91
- Molecule
- Dual-specificity RNA methyltransferase rlmn
- UniProt
- A7ZPW0
- Pockets
- 4 · best druggability 0.83
Structure
1 distinct chain · 38% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual-specificity RNA methyltransferase rlmn | protein | 384 | 38% helix, 18% strand | A7ZPW0 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 191 | 0.83 | 0.97 | 29 | empty |
| 2 | 320 | 0.66 | 0.81 | 38 | empty |
| 3 | 203 | 0.46 | 0.74 | 27 | empty |
| 4 | 104 | 0.41 | 0.77 | 22 | empty |
Compared structures
- 5HR6 · X-ray crystal structure of C118A RlmN with cross-linked tRNA purified from Escherichia… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 5HR6 · X-ray crystal structure of C118A rlmn with cross-linked tRNA purified from escherichia… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 5HR7 · X-ray crystal structure of C118A rlmn from escherichia COLI with cross-linked in vitro… · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 5HR7 · X-ray crystal structure of C118A RlmN from Escherichia coli with cross-linked in vitro… · an experimental structure of the same protein · chain A against B, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7ZPW0
- Elsewhere: UniProt A7ZPW0 · AlphaFold DB A7ZPW0
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