UniProt A7ZPW0
Dual-specificity RNA methyltransferase RlmN (A7ZPW0)
Dual-specificity RNA methyltransferase RlmN (UniProt A7ZPW0), EC 2.1.1.192: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- A7ZPW0
- Protein
- Dual-specificity RNA methyltransferase RlmN
- EC
- 2.1.1.192
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 15 · 2 records with a druggable one
Structures
5 records of A7ZPW0 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HR6 | X-ray crystal structure of C118A RlmN with cross-linked tRNA purified from Escherichia coli | x-ray diffraction | A, B | SF4, 5AD, MG | — |
| 5HR6 | X-ray crystal structure of C118A rlmn with cross-linked tRNA purified from escherichia COLI | x-ray diffraction | A, B | — | — |
| 5HR7 | X-ray crystal structure of C118A RlmN from Escherichia coli with cross-linked in vitro transcribed… | x-ray diffraction | B, A | MG, SF4, 5AD, MET | 11 (best 0.85) |
| 5HR7 | X-ray crystal structure of C118A rlmn from escherichia COLI with cross-linked in vitro transcribed… | x-ray diffraction | B, A | — | — |
| A7ZPW0 | AlphaFold monomer V2.0 prediction for dual-specificity RNA methyltransferase rlmn (A7ZPW0) | predicted | A | — | 4 (best 0.83) |
Ligands
Experiment against prediction
- 5HR6 chain A against the predicted model A7ZPW0: TM-score 1.00, RMSD 0.31 Å
- 5HR6 chain A against the predicted model A7ZPW0: TM-score 1.00, RMSD 0.31 Å
- 5HR7 chain B against the predicted model A7ZPW0: TM-score 0.98, RMSD 1.18 Å
- 5HR7 chain A against the predicted model A7ZPW0: TM-score 0.98, RMSD 1.18 Å
- 5HR7 chain B against the predicted model A7ZPW0: TM-score 0.98, RMSD 1.18 Å
Elsewhere
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