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MolNFT v1 · #376057 · protein

AlphaFold monomer V2.0 prediction for translation initiation factor RLI1 (Q03195)

Q03195: “AlphaFold monomer V2.0 prediction for translation initiation factor RLI1 (Q03195)”. 9 pockets (best druggability 0.73). MolNFT v1 #376057 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q03195
Type
protein
Length
608 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x61c4A405146A0B1058694fd31d36a7b50c9bCbd4
Molecule
Translation initiation factor RLI1
UniProt
Q03195
Pockets
9 · best druggability 0.73

Structure

1 distinct chain · 35% helix, 20% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATranslation initiation factor RLI1protein60835% helix, 20% strandQ03195

Pockets

9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17910.730.7895empty
22000.480.7533empty
31160.430.7619empty
41360.400.7416empty
5910.360.7515empty

Compared structures

  • 3J16 · Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 3J16 · Models of ribosome-bound DOM34P and RLI1P and their ribosomal binding partners · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4CRM · Cryo-EM of a pre-recycling complex with ERF1 and ABCE1 · an experimental structure of the same protein · chain A against P, TM-score 0.91
  • 4CRM · Cryo-EM of a pre-recycling complex with eRF1 and ABCE1 · an experimental structure of the same protein · chain A against P, TM-score 0.91
  • 7A1G · Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex · an experimental structure of the same protein · chain A against x, TM-score 0.72
  • 6ZU9 · Structure of a yeast ABCE1-bound 48S initiation complex · an experimental structure of the same protein · chain A against k, TM-score 0.71
  • 6ZCE · Structure of a yeast ABCE1-bound 43S pre-initiation complex · an experimental structure of the same protein · chain A against k, TM-score 0.71
  • 5LL6 · Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation… · an experimental structure of the same protein · chain A against h, TM-score 0.67
  • 5LL6 · Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation… · an experimental structure of the same protein · chain A against h, TM-score 0.67

Analyse

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