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MolNFT v1 · #365154 · protein

AlphaFold monomer V2.0 prediction for 60S ribosomal protein L30 (P62888)

P62888: “AlphaFold monomer V2.0 prediction for 60S ribosomal protein L30 (P62888)”. 1 pocket (best druggability 0.24). MolNFT v1 #365154 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P62888
Type
protein
Length
115 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xce900C0fF7FC4490Db85F81246504E4B06fbB727
Molecule
60S ribosomal protein L30
UniProt
P62888
Pockets
1 · best druggability 0.24

Structure

1 distinct chain · 45% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A60S ribosomal protein L30protein11545% helix, 17% strandP62888

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1540.240.7212empty

Compared structures

  • 9C3H · Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site. · an experimental structure of the same protein · chain A against Lc, TM-score 0.85
  • 6OLZ · Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP… · an experimental structure of the same protein · chain A against Ac, TM-score 0.85
  • 6OLG · Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with… · an experimental structure of the same protein · chain A against Ac, TM-score 0.85
  • 7OW7 · EIF6-bound large subunit of the human ribosome · an experimental structure of the same protein · chain A against W, TM-score 0.85
  • 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against Lc, TM-score 0.85
  • 8A3D · Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound · an experimental structure of the same protein · chain A against W, TM-score 0.85
  • 8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · an experimental structure of the same protein · chain A against Lc, TM-score 0.85
  • 8QYX · Human 60S ribosomal subunit · an experimental structure of the same protein · chain A against W1, TM-score 0.84
  • 8YOO · Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline · an experimental structure of the same protein · chain A against Lc, TM-score 0.84
  • 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against Lc, TM-score 0.84
  • 7XNY · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells · an experimental structure of the same protein · chain A against Lc, TM-score 0.84
  • 8OHD · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) · an experimental structure of the same protein · chain A against Lc, TM-score 0.84

Analyse

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