GL1X · GenesisL1 explorer

MolNFT v1 · #361356 · protein

AlphaFold monomer V2.0 prediction for 50S ribosomal protein L25 (P9WHB5)

P9WHB5: “AlphaFold monomer V2.0 prediction for 50S ribosomal protein L25 (P9WHB5)”. 1 pocket (best druggability 0.39). MolNFT v1 #361356 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P9WHB5
Type
protein
Length
215 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5f16694a000281156834B5aF7C1a168819505c33
Molecule
50S ribosomal protein L25
UniProt
P9WHB5
Pockets
1 · best druggability 0.39

Structure

1 distinct chain · 24% helix, 41% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A50S ribosomal protein L25protein21524% helix, 41% strandP9WHB5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11090.390.7523empty

Compared structures

  • 7MT7 · Mtb 70S with P and E site tRNAs · an experimental structure of the same protein · chain A against V, TM-score 0.80
  • 7MSC · Mtb 70SIC in complex with MtbEttA at Pre_R0 state · an experimental structure of the same protein · chain A against V, TM-score 0.80
  • 7MT2 · Mtb 70S initiation complex · an experimental structure of the same protein · chain A against V, TM-score 0.80
  • 7MSM · Mtb 70SIC in complex with MtbEttA at Trans_R0 state · an experimental structure of the same protein · chain A against V, TM-score 0.79
  • 7MSH · Mtb 70SIC in complex with MtbEttA at Pre_R1 state · an experimental structure of the same protein · chain A against V, TM-score 0.79
  • 7MT3 · Mtb 70S with P/E tRNA · an experimental structure of the same protein · chain A against V, TM-score 0.78
  • 7MSZ · Mtb 70SIC in complex with MtbEttA at Trans_R1 state · an experimental structure of the same protein · chain A against V, TM-score 0.78
  • 7KGB · CryoEM structure of A2296-methylated Mycobacterium tuberculosis ribosome bound with SEQ-9 · an experimental structure of the same protein · chain A against V, TM-score 0.43

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