AlphaFold monomer V2.0 prediction for 60S ribosomal protein L21 (P46778)

Structure

1 distinct chain · 20% helix, 21% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8A3D · Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound · an experimental structure of the same protein · chain A against N, TM-score 0.96
• 8OHD · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 8OJ8 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 8XSX · Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 8K2C · Cryo-EM structure of the human 80S ribosome with Tigecycline · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 8OJ0 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 8QYX · Human 60S ribosomal subunit · an experimental structure of the same protein · chain A against N1, TM-score 0.96
• 8YOO · Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 8XSY · Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S… · an experimental structure of the same protein · chain A against LT, TM-score 0.96
• 9GMO · eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 · an experimental structure of the same protein · chain A against N, TM-score 0.96
• 8OJ5 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) · an experimental structure of the same protein · chain A against LT, TM-score 0.96

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P46778
• Elsewhere: UniProt P46778 · AlphaFold DB P46778