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MolNFT v1 · #354782 · protein

AlphaFold monomer V2.0 prediction for 60S ribosomal protein L18 (Q07020)

Q07020: “AlphaFold monomer V2.0 prediction for 60S ribosomal protein L18 (Q07020)”. 2 pockets (best druggability 0.30). MolNFT v1 #354782 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q07020
Type
protein
Length
188 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9073C46348542FfE4327c3F363F9B51B22058e75
Molecule
60S ribosomal protein L18
UniProt
Q07020
Pockets
2 · best druggability 0.30

Structure

1 distinct chain · 34% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A60S ribosomal protein L18protein18834% helix, 16% strandQ07020

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1650.300.7414empty
2660.270.7216empty

Compared structures

  • 7OW7 · EIF6-bound large subunit of the human ribosome · an experimental structure of the same protein · chain A against K, TM-score 0.98
  • 8OHD · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8G61 · mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8QYX · Human 60S ribosomal subunit · an experimental structure of the same protein · chain A against K1, TM-score 0.98
  • 8UKB · In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8K2C · Cryo-EM structure of the human 80S ribosome with Tigecycline · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8OJ5 · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (in-vitro reconstitution) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 7XNX · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 7XNY · High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 6LU8 · Cryo-EM structure of a human pre-60S ribosomal subunit - state A · an experimental structure of the same protein · chain A against Z, TM-score 0.98

Analyse

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