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AlphaFold monomer V2.0 prediction for 60S ribosomal protein L18 (Q07020)

Analyse AlphaFold monomer V2.0 prediction for 60S ribosomal protein L18 (Q07020) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q07020
Type
protein
Length
188 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9073C46348542FfE4327c3F363F9B51B22058e75
Molecule
60S ribosomal protein L18
UniProt
Q07020
Pockets
2 · best druggability 0.30

Structure

1 distinct chain · 34% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A60S ribosomal protein L18protein18834% helix, 16% strandQ07020

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1650.300.7414empty
2660.270.7216empty

Compared structures

  • 7OW7 · EIF6-bound large subunit of the human ribosome · an experimental structure of the same protein · chain A against K, TM-score 0.98
  • 8G5Z · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8A3D · Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound · an experimental structure of the same protein · chain A against K, TM-score 0.98
  • 8OHD · 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8G61 · mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8QYX · Human 60S ribosomal subunit · an experimental structure of the same protein · chain A against K1, TM-score 0.98
  • 8UKB · In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8XSX · Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 · an experimental structure of the same protein · chain A against LQ, TM-score 0.98
  • 8K2C · Cryo-EM structure of the human 80S ribosome with Tigecycline · an experimental structure of the same protein · chain A against LQ, TM-score 0.98

Analyse

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