GL1X · GenesisL1 explorer

MolNFT v1 · #348359 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase rkp (Q9SIZ8)

Q9SIZ8: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase rkp (Q9SIZ8)”. 16 pockets (best druggability 0.81). MolNFT v1 #348359 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9SIZ8
Type
protein
Length
1,280 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
Molecule
E3 ubiquitin-protein ligase rkp
UniProt
Q9SIZ8
Pockets
16 · best druggability 0.81

Structure

1 distinct chain · 49% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AE3 ubiquitin-protein ligase rkpprotein128049% helix, 9% strandQ9SIZ8

Pockets

16 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111170.810.82108empty
211520.790.80117empty
32130.610.8239empty
41450.590.8321empty
51900.530.7829empty

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