MolNFT v1 · #346125 · protein
AlphaFold monomer V2.0 prediction for ribosome-inactivating protein alpha-trichosanthin (P09989)
P09989: “AlphaFold monomer V2.0 prediction for ribosome-inactivating protein alpha-trichosanthin (P09989)”. 2 pockets (best druggability 0.62). MolNFT v1 #346125 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P09989
- Type
- protein
- Length
- 289 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x02928767Cd38aeb0E96b8eac0D163d47785dC64E
- Molecule
- Ribosome-inactivating protein alpha-trichosanthin
- UniProt
- P09989
- Pockets
- 2 · best druggability 0.62
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosome-inactivating protein alpha-trichosanthin | protein | 289 | 36% helix, 21% strand | P09989 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 349 | 0.62 | 0.78 | 41 | empty |
| 2 | 59 | 0.31 | 0.75 | 13 | empty |
Compared structures
- 1NLI · Complex of [E160A-E189A] trichosanthin and adenine · an experimental structure of the same protein · chain A against A, TM-score 0.86
- 1NLI · Complex of [E160A-E189A] trichosanthin and adenine · an experimental structure of the same protein · chain A against A, TM-score 0.86
- 1GIS · A TRICHOSANTHIN(TCS) MUTANT(E85Q) complex structure with… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 1GIS · A TRICHOSANTHIN(TCS) MUTANT(E85Q) complex structure with 2'-deoxy… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 2VS6 · K173A, R174A, K177A-trichosanthin · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 2VS6 · K173A, R174A, K177A-trichosanthin · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 1MRJ · Studies on crystal structures active center geometry and depurine mechanism of two… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 1MRJ · Studies on crystal structures active center geometry and depurine mechanism of two… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 1MRK · Studies on crystal structures active center geometry and depurine mechanism of two… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 1MRK · Studies on crystal structures active center geometry and depurine mechanism of two… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 1QD2 · Crystal structure of the complex of trichosanthin with adenine, obtained from… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 1QD2 · Crystal structure of the complex of trichosanthin with adenine, obtained from… · an experimental structure of the same protein · chain A against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09989
- Elsewhere: UniProt P09989 · AlphaFold DB P09989
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