UniProt P09989
Ribosome-inactivating protein alpha-trichosanthin (P09989)
Ribosome-inactivating protein alpha-trichosanthin (UniProt P09989): 22 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P09989
- Protein
- Ribosome-inactivating protein alpha-trichosanthin
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
23 records of P09989 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GIS | A TRICHOSANTHIN(TCS) MUTANT(E85Q) complex structure with 2'-deoxy-adenosin-5'-monophosphate | x-ray diffraction | A | — | — |
| 1GIS | A TRICHOSANTHIN(TCS) MUTANT(E85Q) complex structure with 2'-deoxy- adenosin-5'-monophosphate | x-ray diffraction | A | — | — |
| 1GIU | A TRICHOSANTHIN(TCS) MUTANT(E85R) complex structure with adenine | x-ray diffraction | A | — | — |
| 1GIU | A TRICHOSANTHIN(TCS) MUTANT(E85R) complex structure with adenine | x-ray diffraction | A | — | — |
| 1J4G | crystal structure analysis of the trichosanthin delta C7 | x-ray diffraction | A, B, C, D | — | — |
| 1J4G | Crystal structure analysis of the trichosanthin delta C7 | x-ray diffraction | A, B, C, D | — | — |
| 1MRJ | Studies on crystal structures active center geometry and depurine mechanism of two… | x-ray diffraction | A | — | — |
| 1MRJ | Studies on crystal structures active center geometry and depurine mechanism of two… | x-ray diffraction | A | — | — |
| 1MRK | Studies on crystal structures active center geometry and depurine mechanism of two… | x-ray diffraction | A | — | — |
| 1MRK | Studies on crystal structures active center geometry and depurine mechanism of two… | x-ray diffraction | A | — | — |
| 1NLI | Complex of [E160A-E189A] trichosanthin and adenine | x-ray diffraction | A | — | — |
| 1NLI | Complex of [E160A-E189A] trichosanthin and adenine | x-ray diffraction | A | — | — |
| 1QD2 | Crystal structure of the complex of trichosanthin with adenine, obtained from trichosanthin… | x-ray diffraction | A | — | — |
| 1QD2 | Crystal structure of the complex of trichosanthin with adenine, obtained from trichosanthin… | x-ray diffraction | A | — | — |
| 1TCS | Crystal structure of trichosanthin-NADPH complex at 1.7 ångströms resolution reveals active-site… | x-ray diffraction | A | — | — |
| 1TCS | Crystal structure of trichosanthin-NADPH complex at 1.7 ångströms resolution reveals active-site… | x-ray diffraction | A | — | — |
| 2JDL | Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin | x-ray diffraction | A, B | — | — |
| 2JDL | Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin | x-ray diffraction | A, B | — | — |
| 2JJR | V232K, N236D-trichosanthin | x-ray diffraction | A | — | — |
| 2JJR | V232K, N236D-trichosanthin | x-ray diffraction | A | — | — |
| 2VS6 | K173A, R174A, K177A-trichosanthin | x-ray diffraction | A, B | — | — |
| 2VS6 | K173A, R174A, K177A-trichosanthin | x-ray diffraction | A, B | — | — |
| P09989 | AlphaFold monomer V2.0 prediction for ribosome-inactivating protein alpha-trichosanthin (P09989) | predicted | A | — | 2 (best 0.62) |
Experiment against prediction
- 1NLI chain A against the predicted model P09989: TM-score 1.00, RMSD 0.30 Å
- 1NLI chain A against the predicted model P09989: TM-score 1.00, RMSD 0.30 Å
- 1MRJ chain A against the predicted model P09989: TM-score 1.00, RMSD 0.33 Å
- 1MRJ chain A against the predicted model P09989: TM-score 1.00, RMSD 0.33 Å
- 1MRK chain A against the predicted model P09989: TM-score 1.00, RMSD 0.34 Å
- 1MRK chain A against the predicted model P09989: TM-score 1.00, RMSD 0.34 Å
- 1QD2 chain A against the predicted model P09989: TM-score 1.00, RMSD 0.38 Å
- 1QD2 chain A against the predicted model P09989: TM-score 1.00, RMSD 0.38 Å
- 1GIU chain A against the predicted model P09989: TM-score 1.00, RMSD 0.41 Å
- 1GIU chain A against the predicted model P09989: TM-score 1.00, RMSD 0.41 Å
Elsewhere
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