MolNFT v1 · #346078 · protein
AlphaFold monomer V2.0 prediction for receptor-interacting SERINE/THREONINE-protein kinase 4 (Q9ERK0)
Q9ERK0: “AlphaFold monomer V2.0 prediction for receptor-interacting SERINE/THREONINE-protein kinase 4 (Q9ERK0)”. 7 pockets (best druggability 0.75). MolNFT v1 #346078 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9ERK0
- Type
- protein
- Length
- 786 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3a113053749Cc34e93243C969a73b8FE780ca633
- Molecule
- Receptor-interacting SERINE/THREONINE-protein kinase 4
- UniProt
- Q9ERK0
- Pockets
- 7 · best druggability 0.75
Structure
1 distinct chain · 40% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Receptor-interacting SERINE/THREONINE-protein kinase 4 | protein | 786 | 40% helix, 7% strand | Q9ERK0 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1004 | 0.75 | 0.78 | 71 | empty |
| 2 | 956 | 0.75 | 0.78 | 79 | empty |
| 3 | 338 | 0.59 | 0.77 | 35 | empty |
| 4 | 120 | 0.47 | 0.79 | 22 | empty |
| 5 | 148 | 0.44 | 0.75 | 18 | empty |
Compared structures
- 5WNJ · Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNJ · Crystal structure of murine receptor-interacting protein kinase 4 (RIPK4) D143N in… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNK · Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNK · Crystal structure of murine receptor-interacting protein 4 (RIPK4) D143N bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNM · Crystal structure of murine receptor-interacting protein 4 (RIPK4) D143N bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNM · Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNI · Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNI · Crystal structure of murine receptor-interacting protein kinase 4 (RIPK4) D143N in… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNL · Crystal structure of murine receptor-interacting protein 4 (RIPK4) D143N bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 5WNL · Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to… · an experimental structure of the same protein · chain A against A, TM-score 0.33
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ERK0
- Elsewhere: UniProt Q9ERK0 · AlphaFold DB Q9ERK0
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