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MolNFT v1 · #346011 · protein

AlphaFold monomer V2.0 prediction for ribosome-inactivating protein momordin I (P16094)

P16094: “AlphaFold monomer V2.0 prediction for ribosome-inactivating protein momordin I (P16094)”. 2 pockets (best druggability 0.57). MolNFT v1 #346011 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P16094
Type
protein
Length
286 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xa9d91429a19641abBA7FEA36c01c33066832ba58
Molecule
Ribosome-inactivating protein momordin I
UniProt
P16094
Pockets
2 · best druggability 0.57

Structure

1 distinct chain · 37% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosome-inactivating protein momordin Iprotein28637% helix, 22% strandP16094

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13590.570.7646empty
2790.340.7517empty

Compared structures

  • 5CF9 · Cleavage of nicotinamide adenine dinucleotide by the ribosome inactivating protein of… · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 4YP2 · Cleavage of nicotinamide adenine dinucleotides by the ribosome inactivating protein from… · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 4YP2 · Cleavage of nicotinamide adenine dinucleotides by the ribosome inactivating protein from… · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 1AHA · The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal… · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 1AHA · The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal… · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 1MOM · Crystal structure of momordin, a type I ribosome inactivating protein from the seeds of… · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 1MOM · Crystal structure of momordin, a type I ribosome inactivating protein from the seeds of… · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 6LOW · Crystal structure of alpha-momorcharin in complex with gmp · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 6LOW · crystal structure of alpha-momorcharin in complex with GMP · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 6LOQ · Crystal structure of alpha-momorcharin in complex with camp · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 6LOQ · crystal structure of alpha-momorcharin in complex with cAMP · an experimental structure of the same protein · chain A against A, TM-score 0.86
  • 1AHC · The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal… · an experimental structure of the same protein · chain A against A, TM-score 0.86

Analyse

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