MolNFT v1 · #342564 · protein

AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 18 (Q8K0Q5)

Q8K0Q5: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 18 (Q8K0Q5)”. 10 pockets (best druggability 0.71). MolNFT v1 #342564 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8K0Q5
Type: protein
Length: 663 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0D671490EE06E75975e90D7F99F73B20BE618744
Molecule: Rho GTPase-activating protein 18
UniProt: Q8K0Q5
Pockets: 10 · best druggability 0.71

Structure

1 distinct chain · 46% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 18	protein	663	46% helix, 6% strand	Q8K0Q5

Pockets

10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	497	0.71	0.81	52	empty
2	331	0.59	0.77	34	empty
3	61	0.57	0.89	22	empty
4	317	0.52	0.74	32	empty
5	272	0.51	0.74	42	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8K0Q5
Elsewhere: UniProt Q8K0Q5 · AlphaFold DB Q8K0Q5

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