Research workbench
AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 18 (Q8K0Q5)
Analyse AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 18 (Q8K0Q5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8K0Q5
- Type
- protein
- Length
- 663 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Rho GTPase-activating protein 18
- UniProt
- Q8K0Q5
- Pockets
- 10 · best druggability 0.71
Structure
1 distinct chain · 46% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho GTPase-activating protein 18 | protein | 663 | 46% helix, 6% strand | Q8K0Q5 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 497 | 0.71 | 0.81 | 52 | empty |
| 2 | 331 | 0.59 | 0.77 | 34 | empty |
| 3 | 61 | 0.57 | 0.89 | 22 | empty |
| 4 | 317 | 0.52 | 0.74 | 32 | empty |
| 5 | 272 | 0.51 | 0.74 | 42 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8K0Q5
- Elsewhere: UniProt Q8K0Q5 · AlphaFold DB Q8K0Q5
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