MolNFT v1 · #342538 · protein
AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 6 (O43182)
O43182: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 6 (O43182)”. 9 pockets (best druggability 0.55). MolNFT v1 #342538 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43182
- Type
- protein
- Length
- 974 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xE498A46d2e1B852A3eB35a100fb5E0a679D487dA
- Molecule
- Rho GTPase-activating protein 6
- UniProt
- O43182
- Pockets
- 9 · best druggability 0.55
Structure
1 distinct chain · 26% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho GTPase-activating protein 6 | protein | 974 | 26% helix, 2% strand | O43182 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 340 | 0.55 | 0.74 | 39 | empty |
| 2 | 301 | 0.54 | 0.75 | 26 | empty |
| 3 | 296 | 0.53 | 0.75 | 23 | empty |
| 4 | 130 | 0.48 | 0.79 | 20 | empty |
| 5 | 166 | 0.48 | 0.77 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43182
- Elsewhere: UniProt O43182 · AlphaFold DB O43182
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