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AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 6 (O43182)

Analyse AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 6 (O43182) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O43182
Type
protein
Length
974 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xE498A46d2e1B852A3eB35a100fb5E0a679D487dA
Molecule
Rho GTPase-activating protein 6
UniProt
O43182
Pockets
9 · best druggability 0.55

Structure

1 distinct chain · 26% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARho GTPase-activating protein 6protein97426% helix, 2% strandO43182

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13400.550.7439empty
23010.540.7526empty
32960.530.7523empty
41300.480.7920empty
51660.480.7720empty

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