MolNFT v1 · #342535 · protein
AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 4 (P98171)
P98171: “AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 4 (P98171)”. 5 pockets (best druggability 0.56). MolNFT v1 #342535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P98171
- Type
- protein
- Length
- 946 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Rho GTPase-activating protein 4
- UniProt
- P98171
- Pockets
- 5 · best druggability 0.56
Structure
1 distinct chain · 60% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rho GTPase-activating protein 4 | protein | 946 | 60% helix, 3% strand | P98171 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 162 | 0.56 | 0.81 | 24 | empty |
| 2 | 244 | 0.55 | 0.77 | 19 | empty |
| 3 | 99 | 0.41 | 0.77 | 16 | empty |
| 4 | 71 | 0.34 | 0.76 | 14 | empty |
| 5 | 51 | 0.30 | 0.76 | 14 | empty |
Compared structures
- 2EPD · Solution structure of SH3 domain in rho-GTPase-activating protein 4 · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2EPD · Solution structure of SH3 domain in Rho-GTPase-activating protein 4 · an experimental structure of the same protein · chain A against A, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P98171
- Elsewhere: UniProt P98171 · AlphaFold DB P98171
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