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AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 4 (P98171)

Analyse AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 4 (P98171) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P98171
Type: protein
Length: 946 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf4ED13986579E8e227b3ED6c02276c648754EC27
Molecule: Rho GTPase-activating protein 4
UniProt: P98171
Pockets: 5 · best druggability 0.56

Structure

1 distinct chain · 60% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rho GTPase-activating protein 4	protein	946	60% helix, 3% strand	P98171

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	162	0.56	0.81	24	empty
2	244	0.55	0.77	19	empty
3	99	0.41	0.77	16	empty
4	71	0.34	0.76	14	empty
5	51	0.30	0.76	14	empty

Compared structures

2EPD · Solution structure of SH3 domain in rho-GTPase-activating protein 4 · an experimental structure of the same protein · chain A against A, TM-score 0.07
2EPD · Solution structure of SH3 domain in Rho-GTPase-activating protein 4 · an experimental structure of the same protein · chain A against A, TM-score 0.07

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P98171
Elsewhere: UniProt P98171 · AlphaFold DB P98171

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