MolNFT v1 · #342522 · protein
AlphaFold monomer V2.0 prediction for GTP-binding protein rheb (Q15382)
Q15382: “AlphaFold monomer V2.0 prediction for GTP-binding protein rheb (Q15382)”. 2 pockets (best druggability 0.52). MolNFT v1 #342522 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15382
- Type
- protein
- Length
- 184 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xdF2b063d4B94F3f46D117B1af99A846bD4a59284
- Molecule
- GTP-binding protein rheb
- UniProt
- Q15382
- Pockets
- 2 · best druggability 0.52
Structure
1 distinct chain · 39% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GTP-binding protein rheb | protein | 184 | 39% helix, 26% strand | Q15382 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 160 | 0.52 | 0.79 | 30 | empty |
| 2 | 67 | 0.33 | 0.76 | 18 | empty |
Compared structures
- 1XTS · Structure of small GTPase human rheb in complex with GTP · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1XTS · Structure of small GTPase human Rheb in complex with GTP · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1XTR · Structure of small GTPase human rheb in complex with gppnhp · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1XTR · Structure of small GTPase human Rheb in complex with GppNHp · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 7BTD · Crystal structure of Rheb Y35N mutant bound to GppNHp · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 7BTD · Crystal structure of rheb Y35N mutant bound to gppnhp · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 7BTC · Crystal structure of rheb Y35N mutant bound to GDP · an experimental structure of the same protein · chain A against B, TM-score 0.90
- 7BTC · Crystal structure of Rheb Y35N mutant bound to GDP · an experimental structure of the same protein · chain A against B, TM-score 0.90
- 1XTQ · Structure of small GTPase human rheb in complex with GDP · an experimental structure of the same protein · chain A against A, TM-score 0.90
- 1XTQ · Structure of small GTPase human Rheb in complex with GDP · an experimental structure of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15382
- Elsewhere: UniProt Q15382 · AlphaFold DB Q15382
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