MolNFT v1 · #341753 · protein
AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 6 (P49758)
P49758: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 6 (P49758)”. 5 pockets (best druggability 0.70). MolNFT v1 #341753 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49758
- Type
- protein
- Length
- 472 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa62D9E278a4a7e393ABAEF11f424ec107F27E47B
- Molecule
- Regulator of G-protein signaling 6
- UniProt
- P49758
- Pockets
- 5 · best druggability 0.70
Structure
1 distinct chain · 54% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of G-protein signaling 6 | protein | 472 | 54% helix, 4% strand | P49758 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 435 | 0.70 | 0.81 | 45 | empty |
| 2 | 161 | 0.55 | 0.81 | 24 | empty |
| 3 | 152 | 0.49 | 0.78 | 21 | empty |
| 4 | 160 | 0.46 | 0.75 | 19 | empty |
| 5 | 52 | 0.36 | 0.79 | 17 | empty |
Compared structures
- 2ES0 · Structure of the regulator of G-protein signaling domain of RGS6 · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2ES0 · Structure of the regulator of G-protein signaling domain of RGS6 · an experimental structure of the same protein · chain A against A, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49758
- Elsewhere: UniProt P49758 · AlphaFold DB P49758
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.