MolNFT v1 · #341736 · protein

AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 3 (Q9DC04)

Q9DC04: “AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 3 (Q9DC04)”. 10 pockets (best druggability 0.58). MolNFT v1 #341736 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9DC04
Type: protein
Length: 966 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
Molecule: Regulator of G-protein signaling 3
UniProt: Q9DC04
Pockets: 10 · best druggability 0.58

Structure

1 distinct chain · 16% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Regulator of G-protein signaling 3	protein	966	16% helix, 9% strand	Q9DC04

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.58	0.91	15	empty
2	234	0.53	0.76	27	empty
3	57	0.52	0.87	14	empty
4	164	0.45	0.75	25	empty
5	132	0.38	0.73	18	empty

Compared structures

1WHD · Solution structure of the PDZ domain of RGS3 · an experimental structure of the same protein · chain A against A, TM-score 0.09
1WHD · Solution structure of the PDZ domain of RGS3 · an experimental structure of the same protein · chain A against A, TM-score 0.09

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9DC04
Elsewhere: UniProt Q9DC04 · AlphaFold DB Q9DC04

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