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AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 3 (Q9DC04)

Analyse AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9DC04
Type
protein
Length
966 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
Molecule
Regulator of G-protein signaling 3
UniProt
Q9DC04
Pockets
10 · best druggability 0.58

Structure

1 distinct chain · 16% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARegulator of G-protein signaling 3protein96616% helix, 9% strandQ9DC04

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1510.580.9115empty
22340.530.7627empty
3570.520.8714empty
41640.450.7525empty
51320.380.7318empty

Compared structures

  • 1WHD · Solution structure of the PDZ domain of RGS3 · an experimental structure of the same protein · chain A against A, TM-score 0.09
  • 1WHD · Solution structure of the PDZ domain of RGS3 · an experimental structure of the same protein · chain A against A, TM-score 0.09

Analyse

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