AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 14 (O43566)

Structure

1 distinct chain · 28% helix, 9% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 2JNU · Solution structure of the rgs domain of human RGS14 · an experimental structure of the same protein · chain A against A, TM-score 0.23
• 2JNU · Solution structure of the RGS domain of human RGS14 · an experimental structure of the same protein · chain A against A, TM-score 0.23
• 2XNS · Crystal structure of human G alpha I1 bound to a designed helical peptide derived from… · an experimental structure of the same protein · chain A against C, TM-score 0.05
• 2XNS · Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From… · an experimental structure of the same protein · chain A against C, TM-score 0.05
• 3ONW · Structure of a G-alpha-i1 mutant with enhanced affinity for the RGS14 GoLoco motif. · an experimental structure of the same protein · chain A against C, TM-score 0.05
• 3ONW · Structure of a G-alpha-I1 mutant with enhanced affinity for the RGS14 goloco motif. · an experimental structure of the same protein · chain A against C, TM-score 0.05
• 3QI2 · A Galpha P-loop mutation prevents transition to the activated state: G42R bound to RGS14… · an experimental structure of the same protein · chain A against C, TM-score 0.04
• 3QI2 · A galpha P-loop mutation prevents transition to the activated state: G42R bound to RGS14… · an experimental structure of the same protein · chain A against C, TM-score 0.04

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O43566
• Elsewhere: UniProt O43566 · AlphaFold DB O43566