MolNFT v1 · #341401 · protein

AlphaFold monomer V2.0 prediction for MHC class II regulatory factor RFX1 (P22670)

P22670: “AlphaFold monomer V2.0 prediction for MHC class II regulatory factor RFX1 (P22670)”. 8 pockets (best druggability 0.80). MolNFT v1 #341401 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P22670
Type: protein
Length: 979 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3f713B4B1650176e30B519F2A58Bd9E365E97fD0
Molecule: MHC class II regulatory factor RFX1
UniProt: P22670
Pockets: 8 · best druggability 0.80

Structure

1 distinct chain · 33% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MHC class II regulatory factor RFX1	protein	979	33% helix, 2% strand	P22670

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	433	0.80	0.88	46	empty
2	381	0.58	0.75	46	empty
3	98	0.43	0.78	20	empty
4	70	0.39	0.79	14	empty
5	110	0.38	0.75	24	empty

Compared structures

1DP7 · Cocrystal structure of rfx-dbd in complex with its cognate X-box binding site · an experimental structure of the same protein · chain A against P, TM-score 0.08
1DP7 · Cocrystal structure of rfx-dbd in complex with its cognate X-box binding site · an experimental structure of the same protein · chain A against P, TM-score 0.08

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22670
Elsewhere: UniProt P22670 · AlphaFold DB P22670

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