Research workbench

AlphaFold monomer V2.0 prediction for MHC class II regulatory factor RFX1 (P22670)

Analyse AlphaFold monomer V2.0 prediction for MHC class II regulatory factor RFX1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P22670
Type: protein
Length: 979 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3f713B4B1650176e30B519F2A58Bd9E365E97fD0
Molecule: MHC class II regulatory factor RFX1
UniProt: P22670
Pockets: 8 · best druggability 0.80

Structure

1 distinct chain · 33% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MHC class II regulatory factor RFX1	protein	979	33% helix, 2% strand	P22670

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	433	0.80	0.88	46	empty
2	381	0.58	0.75	46	empty
3	98	0.43	0.78	20	empty
4	70	0.39	0.79	14	empty
5	110	0.38	0.75	24	empty

Compared structures

1DP7 · Cocrystal structure of rfx-dbd in complex with its cognate X-box binding site · an experimental structure of the same protein · chain A against P, TM-score 0.08
1DP7 · Cocrystal structure of rfx-dbd in complex with its cognate X-box binding site · an experimental structure of the same protein · chain A against P, TM-score 0.08

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22670
Elsewhere: UniProt P22670 · AlphaFold DB P22670

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