MolNFT v1 · #332710 · protein
AlphaFold monomer V2.0 prediction for retinoic acid receptor beta (P22605)
P22605: “AlphaFold monomer V2.0 prediction for retinoic acid receptor beta (P22605)”. 5 pockets (best druggability 0.80). MolNFT v1 #332710 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P22605
- Type
- protein
- Length
- 482 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0410a81A4eBc9e5bc9dD9D5a9718D5FfE2c316Da
- Molecule
- Retinoic acid receptor beta
- UniProt
- P22605
- Pockets
- 5 · best druggability 0.80
Structure
1 distinct chain · 38% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Retinoic acid receptor beta | protein | 482 | 38% helix, 3% strand | P22605 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 177 | 0.80 | 0.95 | 31 | empty |
| 2 | 286 | 0.54 | 0.76 | 35 | empty |
| 3 | 261 | 0.53 | 0.76 | 22 | empty |
| 4 | 252 | 0.53 | 0.76 | 32 | empty |
| 5 | 104 | 0.37 | 0.74 | 16 | empty |
Compared structures
- 1XDK · Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex… · an experimental structure of the same protein · chain A against B, TM-score 0.49
- 1XDK · Crystal structure of the RARBETA/RXRALPHA ligand binding domain heterodimer in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.49
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22605
- Elsewhere: UniProt P22605 · AlphaFold DB P22605
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