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MolNFT v1 · #332316 · protein

AlphaFold monomer V2.0 prediction for RAS-related protein ral-a (P11233)

P11233: “AlphaFold monomer V2.0 prediction for RAS-related protein ral-a (P11233)”. 2 pockets (best druggability 0.53). MolNFT v1 #332316 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P11233
Type
protein
Length
206 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
Molecule
RAS-related protein ral-a
UniProt
P11233
Pockets
2 · best druggability 0.53

Structure

1 distinct chain · 44% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARAS-related protein ral-aprotein20644% helix, 21% strandP11233

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11890.530.7833empty
2590.290.7411empty

Compared structures

  • 1ZC4 · Crystal structure of the ral-binding domain of EXO84 in complex with the active rala · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 1ZC4 · Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 1ZC3 · Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 1ZC3 · Crystal structure of the ral-binding domain of EXO84 in complex with the active rala · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 1UAD · Crystal structure of the RalA-GppNHp-Sec5 Ral-binding domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 1UAD · Crystal structure of the rala-gppnhp-SEC5 ral-binding domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.83
  • 2BOV · Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA… · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 2BOV · Molecular recognition of an ADP-ribosylating clostridium botulinum C3 exoenzyme by rala… · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 6P0J · Crystal structure of GDP-bound human rala · an experimental structure of the same protein · chain A against B, TM-score 0.81
  • 6P0J · Crystal structure of GDP-bound human RalA · an experimental structure of the same protein · chain A against B, TM-score 0.81
  • 2A9K · Crystal structure of the C3bot-NAD-RalA complex reveals a novel type of action of a… · an experimental structure of the same protein · chain A against A, TM-score 0.81
  • 2A9K · Crystal structure of the C3BOT-NAD-rala complex reveals a novel type of action of a… · an experimental structure of the same protein · chain A against A, TM-score 0.81

Analyse

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