MolNFT v1 · #331912 · protein
AlphaFold monomer V2.0 prediction for cell cycle checkpoint protein RAD1 (O60671)
O60671: “AlphaFold monomer V2.0 prediction for cell cycle checkpoint protein RAD1 (O60671)”. 3 pockets (best druggability 0.48). MolNFT v1 #331912 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60671
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x463Be372c11f96eeBDBC4baa0AB3805D50aD7Ccd
- Molecule
- Cell cycle checkpoint protein RAD1
- UniProt
- O60671
- Pockets
- 3 · best druggability 0.48
Structure
1 distinct chain · 21% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell cycle checkpoint protein RAD1 | protein | 282 | 21% helix, 44% strand | O60671 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 92 | 0.48 | 0.82 | 27 | empty |
| 2 | 64 | 0.39 | 0.79 | 13 | empty |
| 3 | 50 | 0.28 | 0.75 | 15 | empty |
Compared structures
- 3A1J · Crystal structure of the human Rad9-Hus1-Rad1 complex · an experimental structure of the same protein · chain A against C, TM-score 0.92
- 3A1J · Crystal structure of the human RAD9-HUS1-RAD1 complex · an experimental structure of the same protein · chain A against C, TM-score 0.92
- 8GNN · Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex · an experimental structure of the same protein · chain A against C, TM-score 0.91
- 8WU8 · Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex · an experimental structure of the same protein · chain A against C, TM-score 0.91
- 3G65 · Crystal Structure of the Human Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 3G65 · Crystal structure of the human RAD9-RAD1-HUS1 DNA damage checkpoint complex · an experimental structure of the same protein · chain A against B, TM-score 0.91
- 6J8Y · Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex · an experimental structure of the same protein · chain A against C, TM-score 0.89
- 6J8Y · Crystal structure of the human RAD9-HUS1-RAD1-rhino complex · an experimental structure of the same protein · chain A against C, TM-score 0.89
- 7Z6H · Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 7Z6H · Structure of DNA-bound human RAD17-rfc clamp loader and 9-1-1 checkpoint clamp · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 3GGR · Crystal Structure of the Human Rad9-Hus1-Rad1 complex · an experimental structure of the same protein · chain A against C, TM-score 0.86
- 3GGR · Crystal structure of the human RAD9-HUS1-RAD1 complex · an experimental structure of the same protein · chain A against C, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60671
- Elsewhere: UniProt O60671 · AlphaFold DB O60671
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