UniProt O60671
Cell cycle checkpoint protein RAD1 (O60671)
Cell cycle checkpoint protein RAD1 (UniProt O60671), EC 3.1.11.2: 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O60671
- Protein
- Cell cycle checkpoint protein RAD1
- EC
- 3.1.11.2
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 19 · 3 records with a druggable one
Structures
12 records of O60671 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3A1J | Crystal structure of the human Rad9-Hus1-Rad1 complex | x-ray diffraction | C | — | — |
| 3A1J | Crystal structure of the human RAD9-HUS1-RAD1 complex | x-ray diffraction | C | — | — |
| 3G65 | Crystal Structure of the Human Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex | x-ray diffraction | B | — | — |
| 3G65 | Crystal structure of the human RAD9-RAD1-HUS1 DNA damage checkpoint complex | x-ray diffraction | B | — | — |
| 3GGR | Crystal Structure of the Human Rad9-Hus1-Rad1 complex | x-ray diffraction | C | — | — |
| 3GGR | Crystal structure of the human RAD9-HUS1-RAD1 complex | x-ray diffraction | C | — | — |
| 6J8Y | Crystal structure of the human RAD9-HUS1-RAD1-rhino complex | x-ray diffraction | C | — | — |
| 7Z6H | Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp | electron microscopy | B, K | AGS | 10 (best 0.85) |
| 7Z6H | Structure of DNA-bound human RAD17-rfc clamp loader and 9-1-1 checkpoint clamp | electron microscopy | B, K | AGS | — |
| 8GNN | Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex | x-ray diffraction | C | — | 4 (best 0.61) |
| 8WU8 | Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex | x-ray diffraction | C | — | 2 (best 0.72) |
| O60671 | AlphaFold monomer V2.0 prediction for cell cycle checkpoint protein RAD1 (O60671) | predicted | A | — | 3 (best 0.48) |
Ligands
- AGS · Phosphothiophosphoric acid-adenylate ester · in 2 records
Experiment against prediction
- 8GNN chain C against the predicted model O60671: TM-score 0.99, RMSD 0.60 Å
- 6J8Y chain C against the predicted model O60671: TM-score 0.99, RMSD 0.66 Å
- 3A1J chain C against the predicted model O60671: TM-score 0.99, RMSD 0.69 Å
- 3A1J chain C against the predicted model O60671: TM-score 0.99, RMSD 0.69 Å
- 8WU8 chain C against the predicted model O60671: TM-score 0.98, RMSD 0.87 Å
- 3G65 chain B against the predicted model O60671: TM-score 0.98, RMSD 0.89 Å
- 3G65 chain B against the predicted model O60671: TM-score 0.98, RMSD 0.89 Å
- 7Z6H chain B against the predicted model O60671: TM-score 0.96, RMSD 1.18 Å
- 7Z6H chain B against the predicted model O60671: TM-score 0.96, RMSD 1.18 Å
- 3GGR chain C against the predicted model O60671: TM-score 0.92, RMSD 1.59 Å
Elsewhere
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