MolNFT v1 · #327676 · protein
AlphaFold monomer V2.0 prediction for CTP synthase (B7MLA1)
B7MLA1: “AlphaFold monomer V2.0 prediction for CTP synthase (B7MLA1)”. 6 pockets (best druggability 0.72). MolNFT v1 #327676 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B7MLA1
- Type
- protein
- Length
- 545 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
- Molecule
- CTP synthase
- UniProt
- B7MLA1
- Pockets
- 6 · best druggability 0.72
Structure
1 distinct chain · 41% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CTP synthase | protein | 545 | 41% helix, 23% strand | B7MLA1 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.72 | 0.96 | 17 | empty |
| 2 | 175 | 0.53 | 0.79 | 31 | empty |
| 3 | 200 | 0.48 | 0.76 | 22 | empty |
| 4 | 90 | 0.38 | 0.77 | 20 | empty |
| 5 | 62 | 0.34 | 0.77 | 16 | empty |
Compared structures
- 8FVE · E coli. CTP synthase in complex with CTP (potassium malonate + 100 mM MgCl2) · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 8FV6 · E coli. CTP synthase in complex with dF-dCTP · an experimental structure of the same protein · chain A against AAA, TM-score 0.95
- 8SBR · E coli. CTP synthase in complex with CTP (sodium malonate + 20 mM MgCl2) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 8FV8 · E coli. CTP synthase in complex with dF-dCTP + ADP · an experimental structure of the same protein · chain A against AAA, TM-score 0.95
- 8FV7 · E coli. CTP synthase in complex with dF-dCTP + ATP · an experimental structure of the same protein · chain A against AAA, TM-score 0.95
- 8FVA · E coli. CTP synthase in complex with F-araCTP · an experimental structure of the same protein · chain A against BBB, TM-score 0.95
- 8FVC · E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 5 mM MgCl2) · an experimental structure of the same protein · chain A against AAA, TM-score 0.95
- 8FVB · E coli. CTP synthase in complex with CTP · an experimental structure of the same protein · chain A against AAA, TM-score 0.95
- 8FV9 · E coli. CTP synthase in complex with F-dCTP · an experimental structure of the same protein · chain A against AAA, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7MLA1
- Elsewhere: UniProt B7MLA1 · AlphaFold DB B7MLA1
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