MolNFT v1 · #326365 · protein
AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (fumarate) (Q4D3W2)
Q4D3W2: “AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (fumarate) (Q4D3W2)”. 2 pockets (best druggability 0.76). MolNFT v1 #326365 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q4D3W2
- Type
- protein
- Length
- 314 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Dihydroorotate dehydrogenase (fumarate)
- UniProt
- Q4D3W2
- Pockets
- 2 · best druggability 0.76
Structure
1 distinct chain · 40% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydroorotate dehydrogenase (fumarate) | protein | 314 | 40% helix, 22% strand | Q4D3W2 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 234 | 0.76 | 0.90 | 42 | empty |
| 2 | 62 | 0.53 | 0.87 | 18 | empty |
Compared structures
- 2E68 · Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 2E68 · Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 3W1L · Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1L · Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1M · Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1M · Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 5EA9 · Crystal Structure of Trypanosoma cruzi Dihydroorotate Dehydrogenase in Complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1A · Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1A · Structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1N · Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1N · Crystal structure of trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 3W1P · Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4D3W2
- Elsewhere: UniProt Q4D3W2 · AlphaFold DB Q4D3W2
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