MolNFT v1 · #320298 · protein
AlphaFold monomer V2.0 prediction for pumilio homolog 2 (Q80U58)
Q80U58: “AlphaFold monomer V2.0 prediction for pumilio homolog 2 (Q80U58)”. 4 pockets (best druggability 0.51). MolNFT v1 #320298 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q80U58
- Type
- protein
- Length
- 1,066 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xEa4199940B4536c738284Ed2bf7052fF3a8B3E53
- Molecule
- Pumilio homolog 2
- UniProt
- Q80U58
- Pockets
- 4 · best druggability 0.51
Structure
1 distinct chain · 25% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pumilio homolog 2 | protein | 1066 | 25% helix, 1% strand | Q80U58 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 265 | 0.51 | 0.74 | 28 | empty |
| 2 | 71 | 0.36 | 0.77 | 15 | empty |
| 3 | 56 | 0.30 | 0.75 | 11 | empty |
| 4 | 50 | 0.26 | 0.73 | 8 | empty |
Compared structures
- 3GVT · Structure and RNA binding of the mouse Pumilio-2 Puf Domain · an experimental structure of the same protein · chain A against A, TM-score 0.32
- 3GVT · Structure and RNA binding of the mouse pumilio-2 puf domain · an experimental structure of the same protein · chain A against A, TM-score 0.32
- 3GVO · Structure and RNA binding of the mouse pumilio-2 puf domain · an experimental structure of the same protein · chain A against A, TM-score 0.31
- 3GVO · Structure and RNA binding of the mouse Pumilio-2 Puf Domain · an experimental structure of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80U58
- Elsewhere: UniProt Q80U58 · AlphaFold DB Q80U58
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