MolNFT v1 · #318221 · protein
AlphaFold monomer V2.0 prediction for protein prenyltransferase alpha subunit repeat-containing protein 1 (Q7Z6K3)
Q7Z6K3: “AlphaFold monomer V2.0 prediction for protein prenyltransferase alpha subunit repeat-containing protein 1…”. 6 pockets (best druggability 0.74). MolNFT v1 #318221 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q7Z6K3
- Type
- protein
- Length
- 402 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Protein prenyltransferase alpha subunit repeat-containing protein 1
- UniProt
- Q7Z6K3
- Pockets
- 6 · best druggability 0.74
Structure
1 distinct chain · 62% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein prenyltransferase alpha subunit repeat-containing protein 1 | protein | 402 | 62% helix, 3% strand | Q7Z6K3 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 711 | 0.74 | 0.79 | 54 | empty |
| 2 | 135 | 0.50 | 0.79 | 17 | empty |
| 3 | 111 | 0.40 | 0.76 | 17 | empty |
| 4 | 61 | 0.33 | 0.76 | 17 | empty |
| 5 | 51 | 0.28 | 0.75 | 11 | empty |
Compared structures
- 6O60 · Crystal structure of GGTASE3-FBXL2-SKP1 complex · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 6O60 · Crystal structure of GGTase3-FBXL2-SKP1 complex · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 6J7F · Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 6J7F · Complex of ggtaseiii, farnesyl-YKT6 (C-terminal methylated), and ggpp · an experimental structure of the same protein · chain A against A, TM-score 0.69
- 6J74 · Complex of ggtaseiii and full-length YKT6 · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 6J74 · Complex of GGTaseIII and full-length Ykt6 · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 6J7X · Complex of ggtaseiii, farnesyl-YKT6, and ggpp · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 6J7X · Complex of GGTaseIII, farnesyl-Ykt6, and GGPP · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 6J6X · Crystal structure of apo ggtaseiii · an experimental structure of the same protein · chain A against A, TM-score 0.67
- 6J6X · Crystal structure of apo GGTaseIII · an experimental structure of the same protein · chain A against A, TM-score 0.67
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7Z6K3
- Elsewhere: UniProt Q7Z6K3 · AlphaFold DB Q7Z6K3
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