MolNFT v1 · #318120 · protein
AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-dependent phosphotransferase system (P37177)
P37177: “AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-dependent phosphotransferase system (P37177)”. 7 pockets (best druggability 0.85). MolNFT v1 #318120 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P37177
- Type
- protein
- Length
- 748 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
- Molecule
- Phosphoenolpyruvate-dependent phosphotransferase system
- UniProt
- P37177
- Pockets
- 7 · best druggability 0.85
Structure
1 distinct chain · 50% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoenolpyruvate-dependent phosphotransferase system | protein | 748 | 50% helix, 17% strand | P37177 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1171 | 0.85 | 0.86 | 109 | empty |
| 2 | 103 | 0.55 | 0.84 | 20 | empty |
| 3 | 112 | 0.41 | 0.76 | 17 | empty |
| 4 | 71 | 0.38 | 0.78 | 13 | empty |
| 5 | 58 | 0.38 | 0.79 | 12 | empty |
Compared structures
- 5T1O · Solution-state NMR and saxs structural ensemble of npr (1-85) in complex with ein-ntr… · an experimental structure of the same protein · chain A against B, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37177
- Elsewhere: UniProt P37177 · AlphaFold DB P37177
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