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AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-dependent phosphotransferase system (P37177)

Analyse AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-dependent… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P37177
Type: protein
Length: 748 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
Molecule: Phosphoenolpyruvate-dependent phosphotransferase system
UniProt: P37177
Pockets: 7 · best druggability 0.85

Structure

1 distinct chain · 50% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphoenolpyruvate-dependent phosphotransferase system	protein	748	50% helix, 17% strand	P37177

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1171	0.85	0.86	109	empty
2	103	0.55	0.84	20	empty
3	112	0.41	0.76	17	empty
4	71	0.38	0.78	13	empty
5	58	0.38	0.79	12	empty

Compared structures

5T1O · Solution-state NMR and saxs structural ensemble of npr (1-85) in complex with ein-ntr… · an experimental structure of the same protein · chain A against B, TM-score 0.31

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P37177
Elsewhere: UniProt P37177 · AlphaFold DB P37177

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