MolNFT v1 · #316815 · protein
AlphaFold monomer V2.0 prediction for DNA replication complex gins protein PSF2 (P40359)
P40359: “AlphaFold monomer V2.0 prediction for DNA replication complex gins protein PSF2 (P40359)”. 4 pockets (best druggability 0.39). MolNFT v1 #316815 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40359
- Type
- protein
- Length
- 213 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF8cD1d8d93E9783063700De244A6e3cf6A195579
- Molecule
- DNA replication complex gins protein PSF2
- UniProt
- P40359
- Pockets
- 4 · best druggability 0.39
Structure
1 distinct chain · 53% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA replication complex gins protein PSF2 | protein | 213 | 53% helix, 6% strand | P40359 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 101 | 0.39 | 0.76 | 16 | empty |
| 2 | 110 | 0.37 | 0.73 | 19 | empty |
| 3 | 61 | 0.32 | 0.75 | 14 | empty |
| 4 | 51 | 0.31 | 0.76 | 15 | empty |
Compared structures
- 8KG6 · Yeast replisome in state I · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 8KG8 · Yeast replisome in state II · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 8W7M · Yeast replisome in state V · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 8KG9 · Yeast replisome in state III · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 8W7S · Yeast replisome in state IV · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 6SKL · Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation… · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 7PMN · S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II) · an experimental structure of the same protein · chain A against B, TM-score 0.86
- 8P62 · S. cerevisiae ssDNA-sCMGE after DNA replication initiation · an experimental structure of the same protein · chain A against I, TM-score 0.85
- 8P63 · S. cerevisiae consensus-sCMGE on ssDNA after DNA replication initiation · an experimental structure of the same protein · chain A against I, TM-score 0.85
- 8P5E · S. cerevisiae nexus-sCMGE after DNA replication initiation · an experimental structure of the same protein · chain A against I, TM-score 0.85
- 8B9C · S. cerevisiae pol alpha - replisome complex · an experimental structure of the same protein · chain A against D, TM-score 0.85
- 8B9B · S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA… · an experimental structure of the same protein · chain A against D, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40359
- Elsewhere: UniProt P40359 · AlphaFold DB P40359
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