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MolNFT v1 · #316781 · protein

AlphaFold monomer V2.0 prediction for DNA replication complex gins protein PSF1 (Q14691)

Q14691: “AlphaFold monomer V2.0 prediction for DNA replication complex gins protein PSF1 (Q14691)”. 2 pockets (best druggability 0.38). MolNFT v1 #316781 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q14691
Type
protein
Length
196 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xAa9dfA3b561daFBbf7989Ffd418937f79dC2347c
Molecule
DNA replication complex gins protein PSF1
UniProt
Q14691
Pockets
2 · best druggability 0.38

Structure

1 distinct chain · 58% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA replication complex gins protein PSF1protein19658% helix, 11% strandQ14691

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1570.380.8014empty
2940.370.7613empty

Compared structures

  • 7PLO · H. sapiens replisome-CUL2/LRR1 complex · an experimental structure of the same protein · chain A against D, TM-score 0.94
  • 6XTX · Cryoem structure of human cmg bound to atpgammas and DNA · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 6XTY · Cryoem structure of human cmg bound to and-1 (cmga) · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 2EHO · Crystal structure of human gins complex · an experimental structure of the same protein · chain A against F, TM-score 0.71
  • 2EHO · Crystal structure of human GINS complex · an experimental structure of the same protein · chain A against F, TM-score 0.71
  • 8OK2 · Bipartite interaction of TOPBP1 with the GINS complex · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 2E9X · The crystal structure of human GINS core complex · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 2E9X · The crystal structure of human gins core complex · an experimental structure of the same protein · chain A against A, TM-score 0.71
  • 2Q9Q · The crystal structure of full length human gins complex · an experimental structure of the same protein · chain A against C, TM-score 0.71
  • 2Q9Q · The crystal structure of full length human GINS complex · an experimental structure of the same protein · chain A against C, TM-score 0.71

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