AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 11 (O00231)

Structure

1 distinct chain · 75% helix, 3% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8USB · Non-substrate-engaged human 26S proteasome with Nub1/FAT10 bound to Rpn1 · an experimental structure of the same protein · chain A against X, TM-score 0.85
• 9E8H · Human proteasome in resting state conformation bound to TXNL1 in backward conformation · an experimental structure of the same protein · chain A against X, TM-score 0.85
• 9E8I · Human proteasome in resting state conformation bound to TXNL1 in Forward conformation · an experimental structure of the same protein · chain A against X, TM-score 0.85
• 5GJQ · Structure of the human 26S proteasome bound to USP14-ubal · an experimental structure of the same protein · chain A against Q, TM-score 0.85
• 5GJR · An atomic structure of the human 26S proteasome · an experimental structure of the same protein · chain A against Q, TM-score 0.85
• 5L4K · The human 26S proteasome lid · an experimental structure of the same protein · chain A against Q, TM-score 0.83
• 5L4K · The human 26S proteasome lid · an experimental structure of the same protein · chain A against Q, TM-score 0.83
• 5M32 · Human 26S proteasome in complex with oprozomib · an experimental structure of the same protein · chain A against l, TM-score 0.83
• 5M32 · Human 26S proteasome in complex with Oprozomib · an experimental structure of the same protein · chain A against l, TM-score 0.83
• 5LN3 · The human 26S proteasome at 6.8 ang. · an experimental structure of the same protein · chain A against Q, TM-score 0.79
• 5LN3 · The human 26S Proteasome at 6.8 Ang. · an experimental structure of the same protein · chain A against Q, TM-score 0.79
• 7W39 · Structure of USP14-bound human 26S proteasome in state EA2.1_UBL · an experimental structure of the same protein · chain A against X, TM-score 0.79

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O00231
• Elsewhere: UniProt O00231 · AlphaFold DB O00231