MolNFT v1 · #312190 · protein
AlphaFold monomer V2.0 prediction for probable proteasome subunit alpha type-7 (P21242)
P21242: “AlphaFold monomer V2.0 prediction for probable proteasome subunit alpha type-7 (P21242)”. 3 pockets (best druggability 0.38). MolNFT v1 #312190 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P21242
- Type
- protein
- Length
- 288 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6164D6eD35868169D8366C56A5C3F4D4aFBfCC1C
- Molecule
- Probable proteasome subunit alpha type-7
- UniProt
- P21242
- Pockets
- 3 · best druggability 0.38
Structure
1 distinct chain · 33% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable proteasome subunit alpha type-7 | protein | 288 | 33% helix, 20% strand | P21242 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.38 | 0.78 | 15 | empty |
| 2 | 68 | 0.38 | 0.78 | 16 | empty |
| 3 | 59 | 0.35 | 0.78 | 12 | empty |
Compared structures
- 7LS5 · Cryo-EM structure of the Pre3-1 20S proteasome core particle · an experimental structure of the same protein · chain A against G, TM-score 0.84
- 4LTC · Crystal structure of yeast 20S proteasome in complex with e carmaphycin analogue 6 · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 3NZW · Crystal structure of the yeast 20S proteasome in complex with 2b · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 2FAK · Crystal structure of Salinosporamide A in complex with the yeast 20S proteasome · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 4JSU · Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:3a · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 3NZJ · Crystal structure of yeast 20S proteasome in complex with ligand 2a · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 3HYE · Crystal structure of 20S proteasome in complex with hydroxylated salinosporamide · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 8U7U · Proteasome 20S Core Particle from Beta 3 D205 deletion · an experimental structure of the same protein · chain A against G, TM-score 0.84
- 4INR · Yeast 20S proteasome in complex with the vinyl sulfone LU102 · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 4JSQ · Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:4e · an experimental structure of the same protein · chain A against F, TM-score 0.84
- 3DY3 · Crystal structure of yeast 20S proteasome in complex with the epimer form of… · an experimental structure of the same protein · chain A against F, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21242
- Elsewhere: UniProt P21242 · AlphaFold DB P21242
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